Publications
The latest updated list of publications by Frans Bianchi can be found here.
- Hoffmann, C., Nagao, T., Tsunoyama, T.A. Tromm, J.V., Logan, C., Nakamura, K., Wang, H., Bianchi, F., van den Bogaart, G., Kusumi, A., Hirabayashi, Y., Milovanovic, D. (2026) Membrane-protein-mediated phase separation orchestrates organelle contact sites. Molecular Cell 86: 135-149. Link; Primary data
- Van den Bogaart, G., Bianchi, F., Frans, M.T. (2025) Methods and kits for detecting proliferating cells. WO Patent WO2025116732A1. Link
- Ioannidis, M., Maassen, S., Boekhoud, L., den Ouden, M., Simioniuc, M., Grijpstra, P., Incarnato, D., Bianchi, F., Bouma, H., van den Bogaart, G. (2025) 4-Hydroxynonenal suppresses IL-10 production during infection. BioRXiv preprint
- De Wit, A.S., Warner, H., Huang, H., Verdoes, M., van den Bogaart, G., Bianchi, F. Inhibition of SHP-1 /2 blocks antigen cross-presentation by human macrophages and dendritic cells. BioRXiv preprint
- Jiang, M., Psoma, A., Lyu, J., Chiariello, M.G., Modderman, R., Bianchi, F., Incarnato, D., Marrink, S.J., Jonkers, I.H., van den Bogaart, G. (2025) Butyrate blocks specific histone acetylation by preventing recruitment of p300 to acetylated histones. BioRXiv preprint
- Chen, T., Psoma, A., Mahajan, S., Ter Beest, M., Linders, P., Franciosa, G., Bianchi, F., van den Bogaart, G., Warner, H. (2025) Phosphorylation of VAMP3 couples IL-6 Exocytosis to dendritic cell activation. J Cell Sci. in press. Pubmed
- Jiang, M., Incarnato, D., Modderman, R., Lazaro, A.A., Jonkers, I.H., Bianchi, F., van den Bogaart, G. (2025) Low butyrate concentrations exert anti-inflammatory and high concentrations exert pro-inflammatory effects on macrophages. J Nutr Biochem. in press. Pubmed; Primary data
- Ioannidis, M., van Dijk, H., Muntjeswerff, E.M., Chirasani, V.R., Warner, H., van den Dool, W., Grijpstra, P., Bianchi, F., Mahata, S.K., van den Bogaart, G. (2025) Inflammation promotes proteolytic processing of the prohormone chromogranin A by macrophages. J Endocr Soc. in press. Link; Primary data
- Jiang, M., Bianchi, F., & van den Bogaart, G. (2025) Protonophore activity of short-chain fatty acids induces their intracellular accumulation and acidification. FEBS Lett. in press. Pubmed; Primary data
- de Wit, A.S., Bianchi, F., & van den Bogaart, G. (2025) Antigen presentation of post-translationally modified peptides in major histocompatibility complexes. Immunol Cell Biol. 103: 161-177. Pubmed
- Warner, H.M., Franciosa, G., van der Borg, G., Coenen, B., Faas, F., Koenig, C., de Boer, R., Classens, R., Maassen, S., Baranov, M.V., Mahajan, S., Dabral, D., Bianchi, F., van Hilten, N., Risselada, H.J., Roos, W.H., Olsen, J., Querol Cano, L., & van den Bogaart, G. (2023) Atypical cofilin signaling drives dendritic cell migration through the extracellular matrix via nuclear deformation Cell Rep. 43: 113866. Pubmed; Primary data; PRIDE phosphoproteomics dataset PXD031056
- Jiang, M, Karsenberg, R., Bianchi, F. & van den Bogaart, G. (2024) CD36 as a double-edged sword in cancer. Immunol. Lett. 265: 7-15. Pubmed.
- Warner, H.M., Chen, T., Mahajan, S., te Beest, M., Linders, P., Franciosa, G., Bianchi, F., & van den Bogaart, G. (2023) Trafficking machinery is rapidly primed to facilitate polarised IL-6 secretion in dendritic cells. BioRXiv preprint
- Warner, H, Franciosa, G., van der Borg, G., Faas, F., Koenig, C., de Boer, R., Classens, R., Maassen, S., Baranov, M.V., Mahajan, S., Dabral, D., Coenen, B., Bianchi, F., van Hilten, N., Risselada, H.J., Roos, W.H., Olsen, J., Querol Cano, L., van den Bogaart, G. (2023) Cofilin-driven nuclear deformation drives dendritic cell migration through the extracellular matrix. BioRXiv preprint
- Frans, M.T., Kuipers, E.M., Bianchi, F. & and van den Bogaart, G. (2023) Unveiling the impact of GOLM1/GP73 on cytokine production in cancer and infectious disease. Immunol. Cell Biol. in press. Link.
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Bazioti, V., La Rose, A.M., Maassen, S., Bianchi, F., de Boer, R., Halmos, B., Dabral, D., Guilbaud, E., Flohr-Svendsen, A., Groenen, A.G., Marmolejo-Garza, A., Koster, M.H., Kloosterhuis, N.J., Havinga, R., Pranger, A.T., Langelaar-Makkinje, M., de Bruin, A., van de Sluis, B., Kohan, A.B., Yvan-Charvet, L., van den Bogaart, G., & Westerterp, M. (2022) T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice. Nat. Commun. 13:3799s.
Pubmed. - Stempels, F.C., de Wit, A.S., Swierstra, M.S., Maassen, S., Bianchi, F., van den Bogaart, G., & Baranov, M.V. (2022) A sensitive and less cytotoxic assay for identification of proliferating T cells based on bioorthogonally-functionalized uridine analogue. J. Immunol. Methods. 502: 113228. Pubmed; Primary data.
- Bilderbeek, R., Baranov, M., van den Bogaart., G., & Bianchi, F. (2022) Transmembrane helices are an overlooked and evolutionarily conserved source of major histocompatibility complex class II epitopes. Front. Immunol. 12: 763044. Link; Code and bioinformatics analysis.
- Baranov, M.V., Bianchi, F., & van den Bogaart, G. (2020) The PIKfyve Inhibitor Apilimod: A Double-Edged Sword against COVID-19. Cells. 10: E30 Pubmed.
- Bianchi, F., & van den Bogaart, G. (2020) Vacuolar escape of foodborne bacterial pathogens. J. Cell Sci. 134: jcs247221 Pubmed.
- Van't Klooster, J.S., Bianchi, F., Doorn, R.B., Lorenzon, M., Lusseveld, J.H., Punter, C.M., & Poolman, B. (2020) Extracellular loops matter - subcellular location and function of the lysine transporter Lyp1 from Saccharomyces cerevisiae. FEBS J. Epub ahead of print. Pubmed.
- Bianchi, F., Van't Klooster, J.S., Ruiz, S.J., & Poolman, B. (2019) Regulation of amino acid transport in Saccharomyces cerevisiae. Microbiol Mol Biol Rev. 83: e00024-19. Pubmed.
- Baranov, M.V., Bianchi, F., Schirmacher, A., van Aart, M.A.C., Maassen, S., Muntjewerff, E.M., Dingjan, I., ter Beest, M., Verdoes, M., Keyser, S.G.L., Bertozzi, C.R., Diederichsen, U., & van den Bogaart, G. (2019) The phosphoinositide kinase PIKfyve promotes cathepsin-S-mediated major histocompatibility complex class II antigen presentation. iScience. 11: 160-177. Pubmed.
- Tutakhel, O.A.Z., Bianchi, F., Smits, D.A., Bindels, R.J.M., Hoenderop, J.G.J., & van der Wijst, J. (2018) Dominant functional role of the novel phosphorylation site S811 in the human renal NaCl cotransporter. FASEB J. 16:fj201701047R. Pubmed.
- Bianchi, F., Syga, L., Moiset, G., Spakman, D., Schavemaker, P.E., Punter, C.M., Seinen, A., van Oijen, A.M., Robinson A., & Poolman, B. (2018) Steric exclusion and protein conformation determine the localization of plasma membrane transporters. Nature Comm. 9: 501.
Link.
- Featured in
Chemisch2Weekblad (Dutch).
- Bianchi, F., Textor, J., & van den Bogaart, G. (2017) Transmembrane helices are an overlooked source of MHC class I epitopes. Front. Immunol. 8: 1118. Pubmed.
- Bianchi, F., Klooster, J.S., Ruiz, S.J., Luck, K., Pols, T., Urbatsch, I.L., Poolman, B. (2016) Asymmetry in inward- and outward-affinity constant of transport explain unidirectional lysine flux in Saccharomyces cerevisiae. Sci. Rep. 6:31443 Pubmed.
- Lloris-Garcerá, P., Bianchi, F., Slusky, J.S., Seppälä, S., Daley, D.O., & von Heijne, G. (2012) Antiparallel dimers of the small multidrug resistance protein EmrE are more stable than parallel dimers. J. Biol. Chem. 287:26052-26059 Pubmed.
- Popov-Čeleketić, D., Bianchi, F., Ruiz, S.J., Meutiawati, F., & Poolman, B. (2016) A Plasma Membrane Association Module in Yeast Amino Acid Transporters. J. Biol. Chem. 291:16024-16037. Pubmed.